The Hepatitis B Virus X Protein Inhibits Thymine DNA Glycosylase Initiated Base Excision Repair

The hepatitis B virus (HBV) genome encodes the X protein (HBx), a ubiquitous transactivator that is required for HBV replication. Expression of the HBx protein has been associated with the development of HBV infection-related hepatocellular carcinoma (HCC). Previously, we generated a 3D structure of...

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Bibliographic Details
Main Authors: van de Klundert, Maarten A. A., van Hemert, Formijn J., Zaaijer, Hans L., Kootstra, Neeltje A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493593/
https://ncbi.nlm.nih.gov/pubmed/23145031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048940
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