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Induction of Brain Microvascular Endothelial Cell Urokinase Expression by Cryptococcus neoformans Facilitates Blood-Brain Barrier Invasion

The invasive ability of the blood-borne fungal pathogen Cryptococcus neoformans can be enhanced through interactions with host plasma components, such as plasminogen. Previously we showed by in vitro studies that plasminogen coats the surface of C. neoformans and is converted to the active serine pr...

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Detalhes bibliográficos
Main Authors: Stie, Jamal, Fox, Deborah
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493525/
https://ncbi.nlm.nih.gov/pubmed/23145170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049402
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