Lipid raft/caveolae signaling is required for Cryptococcus neoformans invasion into human brain microvascular endothelial cells

BACKGROUND: Cryptococcus neoformans has a predilection for central nervous system infection. C. neoformans traversal of the blood brain barrier, composed of human brain microvascular endothelial cells (HBMEC), is the crucial step in brain infection. However, the molecular mechanism of the interactio...

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Autors principals: Long, Min, Huang, Sheng-He, Wu, Chun-Hua, Shackleford, Gregory M, Jong, Ambrose
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308189/
https://ncbi.nlm.nih.gov/pubmed/22316086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-19-19
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