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Blood–brain barrier invasion by Cryptococcus neoformans is enhanced by functional interactions with plasmin

Cryptococcus neoformans can invade the central nervous system through diverse mechanisms. We examined a possible role for host plasma proteases in the neurotropic behaviour of this blood-borne fungal pathogen. Plasminogen is a plasma-enriched zymogen that can passively coat the surface of blood-born...

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Hlavní autoři: Stie, Jamal, Fox, Deborah
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for General Microbiology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352358/
https://ncbi.nlm.nih.gov/pubmed/21998162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.051524-0
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