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Microhomology Directs Diverse DNA Break Repair Pathways and Chromosomal Translocations
Chromosomal structural change triggers carcinogenesis and the formation of other genetic diseases. The breakpoint junctions of these rearrangements often contain small overlapping sequences called “microhomology,” yet the genetic pathway(s) responsible have yet to be defined. We report a simple gene...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3493447/ https://ncbi.nlm.nih.gov/pubmed/23144625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003026 |
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