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Skin tumor promotion by phorbol esters is a two-stage process.

In the semisynthetic compound phorbol 12-retinoate 13-acetate (PRA), the antipromoting principle of vitamin A acid is combined with the structure of a phorbol ester tumor promoter. In skin of NMRI mice, a single topical application of PRA induces skin inflammation, epidermal proliferation, and susta...

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Bibliografiske detaljer
Main Authors: Fürstenberger, G, Berry, D L, Sorg, B, Marks, F
Format: Artigo
Sprog:Inglês
Udgivet: 1981
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC349342/
https://ncbi.nlm.nih.gov/pubmed/6801661
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