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Specific binding of phorbol ester tumor promoters

[20-(3)H]Phorbol 12,13-dibutyrate bound to particulate preparations from chicken embryo fibroblasts in a specific, saturable, reversible fashion. Equilibrium binding occurred with a K(d) of 25 nM; this value is very close to the 50% effective dose (ED(50)), 50 nM, previously determined for the biolo...

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Main Authors: Driedger, Paul E., Blumberg, Peter M.
格式: Artigo
語言:Inglês
出版: 1980
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC348314/
https://ncbi.nlm.nih.gov/pubmed/6965793
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