Modeling of the bryostatins to the phorbol ester pharmacophore on protein kinase C.

The bryostatins are macrocyclic lactones that represent an additional structural class of potent activators of protein kinase C. These marine animal biosynthetic products are of unusual interest because they induce only a subset of the biological responses induced by the phorbol esters. We have now...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Wender, P A, Cribbs, C M, Koehler, K F, Sharkey, N A, Herald, C L, Kamano, Y, Pettit, G R, Blumberg, P M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282151/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3174627/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.19.7197
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!