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A comparative study of recombinant mouse and human apurinic/apyrimidinic endonuclease
Mammalian apurinic/apyrimidinic endonuclease (APE1) initiates the repair of abasic sites (AP-sites), which are highly toxic, mutagenic, and implicated in carcinogenesis. Also, reducing the activity of APE1 protein in cancer cells and tumors sensitizes mammalian tumor cells to a variety of laboratory...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3493166/ https://ncbi.nlm.nih.gov/pubmed/22042551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-011-1142-5 |
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