Soluble heparin-binding EGF-like growth factor (HB-EGF) detected by newly developed immuno-PCR method is a clear-cut serological biomarker for ovarian cancer

Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family of growth factors that bind to and activate the EGF receptor. HB-EGF is synthesized as a membrane-anchored protein (proHB-EGF), and then proteolytically cleaved, resulting in the mitogenically active soluble form. HB-EGF p...

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Detalhes bibliográficos
Principais autores: Kasai, Noriyuki, Kobayashi, Kazuhiro, Shioya, Shinobu, Yoshikawa, Yukitaka, Yotsumoto, Fusanori, Miyamoto, Shingo, Mekada, Eisuke, Enokizono, Junichi
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493029/
https://ncbi.nlm.nih.gov/pubmed/23145209
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