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Effect of antigen-dependent clearance on pharmacokinetics of anti-heparin-binding EGF-like growth factor (HB-EGF) monoclonal antibody

Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family and is an important therapeutic target in some types of human cancers. KM3566 is a mouse anti-HB-EGF monoclonal antibody that neutralizes HB-EGF activity by inhibiting the binding of HB-EGF to its receptors. Based on the r...

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Detaylı Bibliyografya
Yayımlandı:MAbs
Asıl Yazarlar: Kasai, Noriyuki, Yoshikawa, Yukitaka, Enokizono, Junichi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622948/
https://ncbi.nlm.nih.gov/pubmed/25517307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.29792
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