Prolonged exposure to methylglyoxal causes disruption of vascular K(ATP) channel by mRNA instability

Diabetes mellitus is characterized by hyperglycemia and excessive production of intermediary metabolites including methylglyoxal (MGO), a reactive carbonyl species that can lead to cell injuries. Interacting with proteins, lipids, and DNA, excessive MGO can cause dysfunction of various tissues, espe...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Yang, Yang, Li, Shanshan, Konduru, Anuhya S., Zhang, Shuang, Trower, Timothy C., Shi, Weiwei, Cui, Ningren, Yu, Lei, Wang, Yali, Zhu, Daling, Jiang, Chun
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492834/
https://ncbi.nlm.nih.gov/pubmed/22972803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00020.2012
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados