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Targeting 4-1BB (CD137) to enhance CD8 T cell responses with poxviruses and viral antigens
Attenuated vaccinia virus (VACV) vectors are considered prime vaccine candidates for use in immunotherapy of infectious disease. In spite of this, recent data show that the level of attenuation may hamper the efficient generation of protective CD8 T cells. This suggests that additional adjuvant-like...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3492829/ https://ncbi.nlm.nih.gov/pubmed/23162550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00332 |
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