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Swainsonine: an inhibitor of glycoprotein processing.

Swainsonine, an indolizidine alkaloid, inhibits the processing of asparagine-linked glycoproteins in both cell-free extracts and animal cells in culture. Thus, in a liver particulate enzyme preparation, swainsonine at 0.1-1.0 microM inhibited the mannosidase that releases [3H]mannose from a high man...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Elbein, A D, Solf, R, Dorling, P R, Vosbeck, K
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1981
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC349273/
https://ncbi.nlm.nih.gov/pubmed/6801650
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