Swainsonine: an inhibitor of glycoprotein processing.

Swainsonine, an indolizidine alkaloid, inhibits the processing of asparagine-linked glycoproteins in both cell-free extracts and animal cells in culture. Thus, in a liver particulate enzyme preparation, swainsonine at 0.1-1.0 microM inhibited the mannosidase that releases [3H]mannose from a high man...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Elbein, A D, Solf, R, Dorling, P R, Vosbeck, K
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1981
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349273/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6801650/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.12.7393
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