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Inhibition of interferon-mediated induction of indoleamine 2,3-dioxygenase in mouse lung by inhibitors of prostaglandin biosynthesis.

Inhibitors of fatty acid cyclooxygenase such as indomethacin (0.1 mM), phenylbutazone (0.3 mM), and aspirin (1 mM) were found to suppress almost completely the interferon-mediated induction of indoleamine 2,3-dioxygenase in mouse lung slices. However, phenacetin, an anti-inflammatory agent devoid of...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Sayama, S, Yoshida, R, Oku, T, Imanishi, J, Kishida, T, Hayaishi, O
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1981
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349259/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6174971/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.12.7327
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