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Inhibition of interferon-mediated induction of indoleamine 2,3-dioxygenase in mouse lung by inhibitors of prostaglandin biosynthesis.

Inhibitors of fatty acid cyclooxygenase such as indomethacin (0.1 mM), phenylbutazone (0.3 mM), and aspirin (1 mM) were found to suppress almost completely the interferon-mediated induction of indoleamine 2,3-dioxygenase in mouse lung slices. However, phenacetin, an anti-inflammatory agent devoid of...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Sayama, S, Yoshida, R, Oku, T, Imanishi, J, Kishida, T, Hayaishi, O
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1981
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349259/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6174971/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.12.7327
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