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Accelerated junctional rhythm and non-alternans repolarization lability precede ventricular tachycardia in Casq2−/− mice
BACKGROUND: Calsequestrin-2 (CASQ2) is a Ca(2+) buffering protein of myocardial sarcoplasmic reticulum. CASQ2 mutations underlie a form of catecholaminergic polymorphic ventricular tachycardia (CPVT). The CPVT phenotype is recapitulated in Casq2−/− mice. Repolarization lability (RL) - beat-to-beat v...
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| Main Authors: | , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2012
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3492500/ https://ncbi.nlm.nih.gov/pubmed/22860618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1540-8167.2012.02406.x |
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