Cooperative Anti-Invasive Effect of Cdc42/Rac1 Activation and ROCK Inhibition in SW620 Colorectal Cancer Cells with Elevated Blebbing Activity

Rho GTPases are key regulators of tumour cell invasion and therefore constitute attractive targets for the design of anticancer agents. Several strategies have been developed to modulate their increased activities during cancer progression. Interestingly, none of these approaches took into account t...

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Detaylı Bibliyografya
Asıl Yazarlar: de Toledo, Marion, Anguille, Christelle, Roger, Laureline, Roux, Pierre, Gadea, Gilles
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492328/
https://ncbi.nlm.nih.gov/pubmed/23144867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048344
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