Use of the Comet-FISH Assay to Compare DNA Damage and Repair in p53 and hTERT Genes following Ionizing Radiation

The alkaline single cell gel electrophoresis (comet) assay can be combined with fluorescent in situ hybridisation (FISH) methodology in order to investigate the localisation of specific gene domains within an individual cell. The number and position of the fluorescent signal(s) provides information...

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Detalhes bibliográficos
Main Authors: McKenna, Declan J., Doherty, Bernadette A., Downes, C. Stephen, McKeown, Stephanie R., McKelvey-Martin, Valerie J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492288/
https://ncbi.nlm.nih.gov/pubmed/23145163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049364
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