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Sphingosine regulates the NLRP3-inflammasome and IL-1β release from macrophages
Interleukin-1β (IL-1β) is a pro-inflammatory cytokine that regulates inflammatory responses to injury and infection. IL-1β secretion requires the protease caspase-1, which is activated following recruitment to inflammasomes. Endogenous danger-associated molecular patterns (DAMPs) released from necro...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
WILEY-VCH Verlag
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3491674/ https://ncbi.nlm.nih.gov/pubmed/22105559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201142079 |
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