Influenza Virus H5 DNA Vaccination Is Immunogenic by Intramuscular and Intradermal Routes in Humans

Avian influenza virus causes outbreaks in domestic and wild birds around the world, and sporadic human infections have been reported. A DNA vaccine encoding hemagglutinin (HA) protein from the A/Indonesia/5/05 (H5N1) strain was initially tested in two randomized phase I clinical studies. Vaccine Res...

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Autores principales: Ledgerwood, J. E., Hu, Z., Gordon, I. J., Yamshchikov, G., Enama, M. E., Plummer, S., Bailer, R., Pearce, M. B., Tumpey, T. M., Koup, R. A., Mascola, J. R., Nabel, G. J., Graham, B. S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
Materias:
Vaccines
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491556/
https://ncbi.nlm.nih.gov/pubmed/22956656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.05663-11
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