Efficient targeted gene disruption in Xenopus embryos using engineered transcription activator-like effector nucleases (TALENs)

Transcription activator-like effector nucleases (TALENs) are an approach for directed gene disruption and have been proved to be effective in various animal models. Here, we report that TALENs can induce somatic mutations in Xenopus embryos with reliably high efficiency and that such mutations are h...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Lei, Yong, Guo, Xiaogang, Liu, Yun, Cao, Yang, Deng, Yi, Chen, Xiongfeng, Cheng, Christopher H. K., Dawid, Igor B., Chen, Yonglong, Zhao, Hui
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491516/
https://ncbi.nlm.nih.gov/pubmed/23045671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1215421109
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars