Global identification of MLL2-targeted loci reveals MLL2’s role in diverse signaling pathways

Myeloid/lymphoid or mixed-lineage leukemia (MLL)-family genes encode histone lysine methyltransferases that play important roles in epigenetic regulation of gene transcription. MLL genes are frequently mutated in human cancers. Unlike MLL1, MLL2 (also known as ALR/MLL4) and its homolog MLL3 are not...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Guo, Changcun, Chang, Chun-Chi, Wortham, Matthew, Chen, Lee H., Kernagis, Dawn N., Qin, Xiaoxia, Cho, Young-Wook, Chi, Jen-Tsan, Grant, Gerald A., McLendon, Roger E., Yan, Hai, Ge, Kai, Papadopoulos, Nickolas, Bigner, Darell D., He, Yiping
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2012
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491484/
https://ncbi.nlm.nih.gov/pubmed/23045699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208807109
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы