KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation

KMT2D (lysine (K)-specific methyltransferase 2D), formerly named MLL2 (myeloid/lymphoid or mixed-lineage leukemia 2, also known as ALR/MLL4), is a histone methyltransferase that plays an important role in regulating gene transcription. In particular, it targets histone H3 lysine 4 (H3K4), whose meth...

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Autori principali: Guo, Changcun, Chen, Lee H., Huang, Yafen, Chang, Chun-Chi, Wang, Ping, Pirozzi, Christopher J., Qin, Xiaoxia, Bao, Xuhui, Greer, Paula K., McLendon, Roger E., Yan, Hai, Keir, Stephen T., Bigner, Darell D., He, Yiping
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2013
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875776/
https://ncbi.nlm.nih.gov/pubmed/24240169
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