Učitavanje...

O-GlcNAc cycling mutants modulate proteotoxicity in Caenorhabditis elegans models of human neurodegenerative diseases

O-GlcNAcylation is an abundant posttranslational modification in the brain implicated in human neurodegenerative diseases. We have exploited viable null alleles of the enzymes of O-GlcNAc cycling to examine the role of O-GlcNAcylation in well-characterized Caenorhabditis elegans models of neurodegen...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Wang, Peng, Lazarus, Brooke D., Forsythe, Michele E., Love, Dona C., Krause, Michael W., Hanover, John A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491483/
https://ncbi.nlm.nih.gov/pubmed/22988095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205748109
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!