Functional analysis of transcription factor binding sites in human promoters

BACKGROUND: The binding of transcription factors to specific locations in the genome is integral to the orchestration of transcriptional regulation in cells. To characterize transcription factor binding site function on a large scale, we predicted and mutagenized 455 binding sites in human promoters...

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Detalhes bibliográficos
Main Authors: Whitfield, Troy W, Wang, Jie, Collins, Patrick J, Partridge, E Christopher, Aldred, Shelley Force, Trinklein, Nathan D, Myers, Richard M, Weng, Zhiping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491394/
https://ncbi.nlm.nih.gov/pubmed/22951020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2012-13-9-r50
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