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Improving N-Glycan Coverage using HPLC with Electrospray Ionization at Sub-ambient Pressure with Mass Spectrometry

Human serum glycan profiling with mass spectrometry (MS) has been employed to study several disease conditions and is demonstrating promise for e.g. clinical biomarker discovery. However, the low glycan ionization efficiency and the large dynamic range of glycan concentrations in human sera hinder c...

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Sonraí Bibleagrafaíochta
Main Authors: Marginean, Ioan, Kronewitter, Scott R., Moore, Ronald J., Slysz, Gordon W., Monroe, Matthew E., Anderson, Gordon, Tang, Keqi, Smith, Richard D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491124/
https://ncbi.nlm.nih.gov/pubmed/23025344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac301961u
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