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Improving N-Glycan Coverage using HPLC with Electrospray Ionization at Sub-ambient Pressure with Mass Spectrometry
Human serum glycan profiling with mass spectrometry (MS) has been employed to study several disease conditions and is demonstrating promise for e.g. clinical biomarker discovery. However, the low glycan ionization efficiency and the large dynamic range of glycan concentrations in human sera hinder c...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3491124/ https://ncbi.nlm.nih.gov/pubmed/23025344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac301961u |
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