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Knockout of Insulin-Like Growth Factor-1 Receptor Impairs Distal Lung Morphogenesis
BACKGROUND: Insulin-like growth factors (IGF-I and -II) are pleiotropic regulators of somatic growth and development in vertebrate species. Endocrine and paracrine effects of both hormones are mediated by a common IGF type 1 receptor (IGF-1R). Lethal respiratory failure in neonatal IGF-1R knockout m...
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Päätekijät: | , , , , , , , , , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
Public Library of Science
2012
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3491012/ https://ncbi.nlm.nih.gov/pubmed/23139760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048071 |
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