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Free fatty acids induce ER stress and block antiviral activity of interferon alpha against hepatitis C virus in cell culture
BACKGROUND: Hepatic steatosis is recognized as a major risk factor for liver disease progression and impaired response to interferon based therapy in chronic hepatitis C (CHC) patients. The mechanism of response to interferon-alpha (IFN-α) therapy under the condition of hepatic steatosis is unexplor...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3490746/ https://ncbi.nlm.nih.gov/pubmed/22863531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-9-143 |
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