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Corallopyronin A Specifically Targets and Depletes Essential Obligate Wolbachia Endobacteria From Filarial Nematodes In Vivo

Doxycycline and rifampicin deplete essential Wolbachia from filarial nematodes that cause lymphatic filariasis or onchocerciasis, resulting in blocked worm development and death. However, doxycycline is contraindicated for children and pregnant/breastfeeding women, as is rifampicin in the latter gro...

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Bibliographische Detailangaben
Hauptverfasser: Schiefer, Andrea, Schmitz, Alexander, Schäberle, Till F., Specht, Sabine, Lämmer, Christine, Johnston, Kelly L., Vassylyev, Dmitry G., König, Gabriele M., Hoerauf, Achim, Pfarr, Kenneth
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490692/
https://ncbi.nlm.nih.gov/pubmed/22586066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis341
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