Corallopyronin A Specifically Targets and Depletes Essential Obligate Wolbachia Endobacteria From Filarial Nematodes In Vivo

Doxycycline and rifampicin deplete essential Wolbachia from filarial nematodes that cause lymphatic filariasis or onchocerciasis, resulting in blocked worm development and death. However, doxycycline is contraindicated for children and pregnant/breastfeeding women, as is rifampicin in the latter gro...

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Detalhes bibliográficos
Main Authors: Schiefer, Andrea, Schmitz, Alexander, Schäberle, Till F., Specht, Sabine, Lämmer, Christine, Johnston, Kelly L., Vassylyev, Dmitry G., König, Gabriele M., Hoerauf, Achim, Pfarr, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490692/
https://ncbi.nlm.nih.gov/pubmed/22586066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis341
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