Selective loss of antigen-specific Ir gene function in IA mutant B6.C-H-2bm12 is an antigen presenting cell defect.

Immune responses to several soluble antigens were compared between B6.C-H-2bm12 mutant and wild-type B6 mice by using a lymph node T-cell proliferation assay. B6.C-H-2bm12 mice failed to respond to beef insulin whereas other IA gene-controlled responses, such as response to poly(L-Tyr, L-Glu)--poly(...

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Detalles Bibliográficos
Main Authors: Lin, C C, Rosenthal, A S, Passmore, H C, Hansen, T H
Formato: Artigo
Idioma:Inglês
Publicado: 1981
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC349048/
https://ncbi.nlm.nih.gov/pubmed/7031650
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