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Interactions among clonal subpopulations affect stability of the metastatic phenotype in polyclonal populations of B16 melanoma cells.

Analysis of the metastatic properties of clones isolated from mouse B16 melanoma cell lines (B16-F1 and F10) shows extensive cellular heterogeneity and the presence of subpopulations that have widely differing metastatic abilities. This pattern of metastatic heterogeneity is maintained during serial...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Poste, G, Doll, J, Fidler, I J
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1981
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349011/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6947225/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.10.6226
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