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Interactions among clonal subpopulations affect stability of the metastatic phenotype in polyclonal populations of B16 melanoma cells.

Analysis of the metastatic properties of clones isolated from mouse B16 melanoma cell lines (B16-F1 and F10) shows extensive cellular heterogeneity and the presence of subpopulations that have widely differing metastatic abilities. This pattern of metastatic heterogeneity is maintained during serial...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Poste, G, Doll, J, Fidler, I J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349011/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6947225/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.10.6226
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