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Aromatase inhibition remodels the clonal architecture of estrogen-receptor-positive breast cancers

Aromatase inhibitors are used to treat oestrogen-receptor-positive breast cancer. Here, the authors use genomic approaches to analyse tumours before and after neo-adjuvant treatment and find that treatment alters the clonal landscape of the tumours.

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Autors principals: Christopher A. Miller, Yevgeniy Gindin, Charles Lu, Obi L Griffith, Malachi Griffith, Dong Shen, Jeremy Hoog, Tiandao Li, David E. Larson, Mark Watson, Sherri R Davies, Kelly Hunt, Vera J. Suman, Jacqueline Snider, Thomas Walsh, Graham A. Colditz, Katherine DeSchryver, Richard K. Wilson, Elaine R. Mardis, Matthew J. Ellis
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2016-08-01
Col·lecció:Nature Communications
Accés en línia:https://doi.org/10.1038/ncomms12498
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