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Dissecting Structure of Prion Amyloid Fibrils by Hydrogen-Deuterium Exchange Ultraviolet Raman Spectroscopy

The molecular mechanisms underlying structural diversity of amyloid fibrils or prion strains formed within the same primary structure is considered to be one of the most enigmatic questions in prion biology. We report here on the direct characterization of amyloid structures using novel spectroscopi...

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Main Authors: Shashilov, Victor, Xu, Ming, Makarava, Natallia, Savtchenko, Regina, Baskakov, Ilia V., Lednev, Igor K.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490051/
https://ncbi.nlm.nih.gov/pubmed/22681559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp2122455
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