New Insights into the Hendra Virus Attachment and Entry Process from Structures of the Virus G Glycoprotein and Its Complex with Ephrin-B2

Hendra virus and Nipah virus, comprising the genus Henipavirus, are recently emerged, highly pathogenic and often lethal zoonotic agents against which there are no approved therapeutics. Two surface glycoproteins, the attachment (G) and fusion (F), mediate host cell entry. The crystal structures of...

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Hauptverfasser: Xu, Kai, Chan, Yee-Peng, Rajashankar, Kanagalaghatta R., Khetawat, Dimple, Yan, Lianying, Kolev, Momchil V., Broder, Christopher C., Nikolov, Dimitar B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489827/
https://ncbi.nlm.nih.gov/pubmed/23144952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048742
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