New Insights into the Hendra Virus Attachment and Entry Process from Structures of the Virus G Glycoprotein and Its Complex with Ephrin-B2

Hendra virus and Nipah virus, comprising the genus Henipavirus, are recently emerged, highly pathogenic and often lethal zoonotic agents against which there are no approved therapeutics. Two surface glycoproteins, the attachment (G) and fusion (F), mediate host cell entry. The crystal structures of...

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Main Authors: Xu, Kai, Chan, Yee-Peng, Rajashankar, Kanagalaghatta R., Khetawat, Dimple, Yan, Lianying, Kolev, Momchil V., Broder, Christopher C., Nikolov, Dimitar B.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489827/
https://ncbi.nlm.nih.gov/pubmed/23144952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048742
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