Φορτώνει......
Boosting antibody-dependant cellular cytotoxicity against tumor cells with a CD137 stimulatory antibody
Monoclonal antibodies (mAb) induce tumor regression through antibody-dependant cellular cytotoxicity (ADCC). We recently showed that an agonistic anti-CD137 mAb stimulates natural killer (NK) cells which have been activated by a tumor-specific mAb, resulting in increased ADCC against cancer cells.
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
|---|---|
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Landes Bioscience
2012
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3489758/ https://ncbi.nlm.nih.gov/pubmed/23162770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.19974 |
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