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Methotrexate-resistant Chinese hamster ovary cells have amplified a 135-kilobase-pair region that includes the dihydrofolate reductase gene.

For the eventual purpose of isolating and studying a single animal cell replicon, we have developed a methotrexate-resistant Chinese hamster ovary cell line that has amplified an early-replicating DNA sequence approximately 500 times; this sequence includes the gene coding for dihydrofolate reductas...

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Detaylı Bibliyografya
Asıl Yazarlar: Milbrandt, J D, Heintz, N H, White, W C, Rothman, S M, Hamlin, J L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1981
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC348973/
https://ncbi.nlm.nih.gov/pubmed/6273843
Etiketler: Etiketle
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