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Effects on human transcriptome of mutated BRCA1 BRCT domain: A microarray study
BACKGROUND: BRCA1 (breast cancer 1, early onset) missense mutations have been detected in familial breast and ovarian cancers, but the role of these variants in cancer predisposition is often difficult to ascertain. In this work, the molecular mechanisms affected in human cells by two BRCA1 missense...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3489683/ https://ncbi.nlm.nih.gov/pubmed/22646717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-207 |
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