Preserved vascular integrity and enhanced survival following neuropilin-1 inhibition in a mouse model of CD8 T cell-initiated CNS vascular permeability

BACKGROUND: Altered permeability of the blood–brain barrier (BBB) is a feature of numerous neurological conditions including multiple sclerosis, cerebral malaria, viral hemorrhagic fevers and acute hemorrhagic leukoencephalitis. Our laboratory has developed a murine model of CD8 T cell-initiated cen...

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Main Authors: Suidan, Georgette L, Dickerson, Jonathan W, Johnson, Holly L, Chan, Theresa W, Pavelko, Kevin D, Pirko, Istvan, Seroogy, Kim B, Johnson, Aaron J
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2012
Ábhair:
Short Report
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489603/
https://ncbi.nlm.nih.gov/pubmed/22985494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-218
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