Effects of Coptis extract combined with chemotherapeutic agents on ROS production, multidrug resistance, and cell growth in A549 human lung cancer cells

BACKGROUND: Non–small cell lung cancer is associated with high expression of multidrug resistance (MDR) proteins and low production of reactive oxygen species (ROS). Coptis extract (COP), a Chinese medicinal herb, and its major constituent, berberine (BER), have anticancer properties. This study aim...

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Detalhes bibliográficos
Main Authors: He, Chengwei, Rong, Rong, Liu, Jing, Wan, Jianbo, Zhou, Keyuan, Kang, Jing X
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488973/
https://ncbi.nlm.nih.gov/pubmed/22546215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8546-7-11
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