Inhibiting Delta-6 Desaturase Activity Suppresses Tumor Growth in Mice

Recent studies have shown that a tumor-supportive microenvironment is characterized by high levels of pro-inflammatory and pro-angiogenic eicosanoids derived from omega-6 (n−6) arachidonic acid (AA). Although the metabolic pathways (COX, LOX, and P450) that generate these n−6 AA eicosanoids have bee...

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Autori principali: He, Chengwei, Qu, Xiying, Wan, Jianbo, Rong, Rong, Huang, Lili, Cai, Chun, Zhou, Keyuan, Gu, Yan, Qian, Steven Y., Kang, Jing X.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480421/
https://ncbi.nlm.nih.gov/pubmed/23112819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047567
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