Indoleamine 2,3-Dioxygenase and Metabolites Protect Murine Lung Allografts and Impair the Calcium Mobilization of T Cells

The enzyme indoleamine 2,3-dioxygenase (IDO) converts tryptophan into kynurenine metabolites that suppress effector T-cell function. In this study, we investigated IDO and its metabolite, 3-hydroxyanthranilic acid (3HAA), in regulating lung allograft rejection, using a murine orthotopic lung transpl...

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Detaylı Bibliyografya
Asıl Yazarlar: Iken, Khadija, Liu, Kaifeng, Liu, Hanzhong, Bizargity, Peyman, Wang, Liqing, Hancock, Wayne W., Visner, Gary A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Thoracic Society 2012
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488632/
https://ncbi.nlm.nih.gov/pubmed/22517796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2011-0438OC
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