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Pirfenidone Inhibits T Cell Activation, Proliferation, Cytokine and Chemokine Production, and Host Alloresponses

BACKGROUND: We previously showed that pirfenidone, an anti-fibrotic agent, reduces lung allograft injury/rejection. In this study, we tested the hypothesis that pirfenidone has immune modulating activities and evaluated its effects on the function of T cell subsets, which play important roles in all...

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Hlavní autoři: Visner, Gary A., Liu, Fengzhi, Bizargity, Peyman, Liu, Hanzhong, Liu, Kaifeng, Yang, Jun, Wang, Liqing, Hancock, Wayne W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726969/
https://ncbi.nlm.nih.gov/pubmed/19667934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e3181ae3392
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