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Neuron-targeted copolymers with sheddable shielding blocks synthesized using a reducible, RAFT-ATRP double-head agent

Successful adaptation of in vitro optimized polymeric gene delivery systems for in vivo use remains a significant challenge. Most in vivo applications require particles that are sterically stabilized but doing so significantly compromises transfection efficiency of materials shown to be effective in...

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Detalhes bibliográficos
Main Authors: Wei, Hua, Schellinger, Joan G., Chu, David S.H., Pun, Suzie H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488458/
https://ncbi.nlm.nih.gov/pubmed/23013485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3085803
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