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In vivo identification of essential nucleotides in tRNA(Leu) to its functions by using a constructed yeast tRNA(Leu) knockout strain

The fidelity of protein biosynthesis requires the aminoacylation of tRNA with its cognate amino acid catalyzed by aminoacyl-tRNA synthetase with high levels of accuracy and efficiency. Crucial bases in tRNA(Leu) to aminoacylation or editing functions of leucyl-tRNA synthetase have been extensively s...

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Detalhes bibliográficos
Main Authors: Huang, Qian, Yao, Peng, Eriani, Gilbert, Wang, En-Duo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488233/
https://ncbi.nlm.nih.gov/pubmed/22917587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks783
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